Public and Private Cord Blood Banking For Potential Future Transplantation

The current post "Public and Private Cord Blood Banking For Potential Future Transplantation" is the continuation of the first post written in December , concerning  the  article published in Pediatrics Journal “Cord Blood Banking for Potential Future Transplantation”

This medical article is the updated version of the “Cord Blood Banking for Potential Future Transplantation” published in 2007.

It represents a policy statement edited under authority of American Academy of Pediatrics, and contains official position on the public and family cord blood banking.

  1. Several medical organizations worldwide* have a common opinion on supporting donation of cord blood to the public banks.

This pro public bank point of view is taking into consideration the comparison of number of cord blood units released for transplantation from public banks versus those released from family banks (estimated to 1 in several 1000).

Great majority of these cord blood units, especially those released from public banks were used for current standard indications of blood forming stem cell transplantations.

The use of cord blood in the emerging field of regenerative medicine is still considered as experimental treatment.

Although encouraging results were recently reported especially for pediatric neurological diseases such as cerebral palsy, so far stem cell therapy was not validated as a proven efficient standard treatment for none of the diseases for which it was applied.

Therefore the evaluations of several medical organizations worldwide are still focused mainly on the statistics related to current standard indications of blood forming stem cell transplantations.

  1. There is only one exception on the general recommendation of donation to public institution.

Storage of cord blood unit in a family-directed cord blood bank is accepted as exception if a family member is diagnosed with a disease potentially curable by cord blood transplantation.

Such family-directed cord blood banks are usually established within the medical universities or in a few private banks that run sibling or family transplantation programs.

  1. Cord blood units stored in family banks may be used for family members with non malignant conditions only based on a good immunological compatibility between the donor (the child at whose birth the cord blood was harvested) and the recipient (the family member having indication of blood forming stem cell transplantation).

 

  1. Ethical concerns related to private/family banks are raised especially in the European countries.

The most critical opinion regarding family banks are expressed by the Italian Committee for the Proper Use of Umbilical Cord Blood to the Chairman of the Health Commission of the European Parliament.

As a result of these debates the Council of Europe has issued in 2016 a second edition of the brochure “Umbilical cord blood banking - A guide for parents”. 

This brochure were written as an objective and equilibrated educational material for parents to be in order to support them during their decision process regarding cord blood collection at birth of their child.

In order to reach this brochure to every future parents the brochure UE decided to  be mandatory adopted and implemented in all European countries providing family banking services.

 

 

**  American Society for Blood and Marrow Transplantation; International Federation of Gynecology and Obstetrics; United Kingdom’s Royal College of Obstetricians and Gynecologists;  Society of Obstetricians and Gynecologists of Canada; World Marrow Donor Association,  AAP,  American Congress of Obstetricians and Gynecologists;  American Society for Blood and Marrow Transplantation.

Source:

* Shearer WT, Lubin BH, Cairo MS, et alAAP SECTION ON HEMATOLOGY/ONCOLOGY, AAP SECTION ON ALLERGY AND IMMUNOLOGY. Cord Blood Banking for Potential Future Transplantation. Pediatrics. 2017;140(5):e20172695

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