Stem cells banking

Who Can Be Used For a CBU According to Immunological Compatibility?

What kind of tests are performed in order to check the immunological compatibility between the donor and recipient?

HLA typing is a special kind of test which is performed in order to check the immunological compatibility between the donor and recipient.

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Who can be used for a cord blood unit stored in a family bank?

This is one of the frequent questions addressed by the future parents considering to collect and store stem cells at birth of their child.

Before diving into a detailed presentation of this topic is very important to highlight the following 4 basic principles:

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Public and Private Cord Blood Banking For Potential Future Transplantation

This medical article published in Pediatrics Journal in December 2017  is the updated version of the “Cord Blood Banking for Potential Future Transplantation” published in 2007.

It represents a policy statement edited under authority of American Academy of Pediatrics, and contains official position on the public and family cord blood banking.

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Cord Blood Banking for Potential Future Transplantation - What's new? 

Recently an updated version of “Cord Blood Banking for Potential Future Transplantation” policy statement has been published under authority of American Academy of Pediatrics.

Almost 10 years passed since the first version of  “Cord Blood Banking for Potential Future Transplantation” has been published in “Pediatrics” journal.

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Stem cell harvesting at birth

Stem cell harvesting at birth is a simple, noninvasive, painless medical procedure lasting between 30 seconds and 2-3 minutes.

After the birth, the umbilical cord is pulsating for a few minutes (usually between 3-5 minutes). When the last pulsation stops the umbilical cord is clamped and cut off from the newborn.

In the blood vessels of umbilical cord and  the placenta remains in average 50-60 ml of blood, after the clamping and the cutting of  the umbilical cord. 

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Is it an option cord blood collection in preterm infants?

Recommendations of cord blood collection in preterm infants according to Netcord-FACT standards are split in 2 categories, if the procedure is performed while placenta is still in uterus:

  • For public banking, the procedure may be performed only if the pregnancy has a minimum of 34 weeks of gestation
  • For related/family banking, the procedure may be performed at less than 34 weeks’ gestation only “based on an evaluation of infant donor safety by the licensed health care professional responsible for the delivery

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10 aspects to consider about umbilical cord blood banking 

Future parents should make the decision to harvest and store the umbilical cord blood only after a careful and accurate prior informing and not because it is a current trend.

Each couple of parents to be should consider at least the following 10 aspects related with umbilical cord blood banking

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Let’s understand cord blood stem cells banking. 

Umbilical cord blood represents the blood left in the umbilical cord and placenta after the baby is born. The collection is recommended to be performed after the last umbilical cord pulsations of has stopped, umbilical cord is clamped and subsequently cut.

In case that cord blood is not collected this is usually discarded as “biological waste”, along with the umbilical cord and placenta.

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How long can be used stem cells from a stored cord blood unit?

Or in other words, which is the validity term for the viability of stem cells from a frozen umbilical cord blood unit? This is one of the most important questions that both, physicians and parents, who have chosen for cord blood banking would like to have an answer.

23,5 years, this is the current answer which can be given in accordance with published results of medical research on the oldest frozen specimen of umbilical cord blood, available in laboratory from Indiana University School of Medicine (IUSM), Indianapolis, Indiana.

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 Is it an option cord blood collection in preterm infants?

Every year, an estimated 15 million babies are born preterm (before 37 completed weeks of gestation), and this number is rising

The option of cord blood collection in preterm infants is an important aspect to be taken into consideration by licensed health care professional responsible for the baby delivery.

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Stem cell harvesting at birth

Stem cell harvesting at birth is a simple, noninvasive, painless medical procedure lasting between 30 seconds and 2-3 minutes.

There are currently two methods of umbilical cord blood collection, as source of stem cell available at birth.

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